Genes Set Enrichment Analysis (GSEA) results


GSEA on all genes. This analysis is done by day and cell type on list of genes ranked by padj decreasing. The data base use is genes set from Molecular Signatures DataBase (MSigDB) species :

  • species = Mus musculus
  • category C2 = online pathway databases and the biomedical literature curated (more details
  • subcategory = Canonical pathways ,Reactome database Composed by 1604 pathways.

Descriptives statistics


How many pathways are significatives (padj<0.05)

ECs FAPs sCs M1 M2 Neutro NumberPathwayEnrichedByDay
D0 0 71 72 NA NA NA 108
D2 0 78 384 5 11 3 398
D4 115 4 325 4 18 NA 346
D7 3 0 20 NA 0 NA 23
NumberPathwayEnrichedByTypeCell 115 105 495 9 29 3

Inspected Hierarchical Classement of pathway in REACTOME


All condition combined, there are 527 pathway enriched. In this representation only pathway with upper letter are enriched in at least one condition.


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Inspected the repartition of enrichied pathways across days and type cell


Number pathway
Numbers conditions enrichis 1 2 3 4 5 6 7 8
Numbers pathways 254 139 46 28 34 22 3 1

Pathways founds enriched in 8 conditions


Pathways founds enriched in 7 conditions


Pathways founds enriched in 6 conditions


Pathways founds enriched in 5 conditions


Pathways founds enriched in 4 conditions


Pathways founds enriched in 3 conditions


Pathways founds enriched in 2 conditions


Pathways founds enrichired in 1 condition


Table Recapitulatif